Organ transplantation is the surgical procedure in which a healthy organ or tissue is transferred from one person (the donor) to another person (the recipient) whose organ has failed or been damaged. This procedure is commonly performed to replace organs such as the heart, liver, lungs, kidneys, and pancreas. Organ transplantation has greatly improved the quality of life and increased the survival rates of patients with organ failure or diseases. However, there are challenges such as the shortage of organ donors, rejection of the transplanted organ by the recipient's immune system, and the need for lifelong immunosuppressive therapy. Researchers are continuously working on developing new techniques to improve organ transplantation outcomes and overcome these challenges.